Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731454 | 0.79 | EGFR (0.45) | ALDH1A1KDM4EGAAMAPTEGFR | |
| SCHEMBL29953988 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EGAAMAPTPOLB | |
| SCHEMBL6340621 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EGAAMAPTPOLB | |
| SCHEMBL9730856 | 0.78 | MAPT (0.60) | ALDH1A1KDM4EGAAMAPTEGFR | |
| SCHEMBL9730827 | 0.75 | POLB (0.45) | ALDH1A1KDM4EGAAMAPTEGFR | |
| SCHEMBL9665745 | 0.74 | KDM4E (0.46) | ALDH1A1KDM4EGAAMAPTPKM | |
| SCHEMBL9731551 | 0.72 | PDGFRB (0.63) | ALDH1A1KDM4EGAAMAPTEGFR | |
| SCHEMBL9724274 | 0.72 | KDM4E (0.45) | ALDH1A1KDM4EGAAMAPTEGFR | |
| Formamide SCHEMBL9732252 | 0.72 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAAMAPTPOLB | |
| SCHEMBL4418030 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |