Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731088 | 0.88 | KDM4E (0.53) | ALDH1A1KDM4EEGFRGAAMAPT | |
| SCHEMBL29953405 | 0.81 | ESR2 (0.54) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL2446728 | 0.81 | ESR2 (0.54) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL9731551 | 0.80 | PDGFRB (0.63) | ALDH1A1KDM4EEGFRGAAMAPT | |
| SCHEMBL9731167 | 0.76 | KDM4E (0.51) | ALDH1A1KDM4EEGFRGAAMAPT | |
| Formamide SCHEMBL9730938 | 0.75 | PDGFRB (0.48) | ALDH1A1KDM4EGAAMAPTESR2 | |
| SCHEMBL9731187 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4EEGFRGAAMAPT | |
| SCHEMBL9731363 | 0.73 | MAPT (0.49) | ALDH1A1KDM4EEGFRGAAMAPT | |
| SCHEMBL9731098 | 0.73 | EGFR (0.49) | ALDH1A1KDM4EEGFRGAAMAPT | |
| SCHEMBL9731151 | 0.72 | EGFR (0.46) | ALDH1A1KDM4EEGFRGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |