Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ESRRB | O95718 | 1/20 | 0.33 |
| ▸ | ESRRA | P11474 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9731093 | 0.88 | PARP1 (0.43) | PDGFRBPDGFRAESR2PARP1KMT2A | |
| SCHEMBL29953405 | 0.82 | ESR2 (0.54) | PDGFRBPDGFRAESR2KMT2AALDH1A1 | |
| SCHEMBL2446728 | 0.82 | ESR2 (0.54) | PDGFRBPDGFRAESR2KMT2AALDH1A1 | |
| Formamide SCHEMBL9731556 | 0.80 | PDGFRB (0.56) | PDGFRBPDGFRAPARP1KMT2AALDH1A1 | |
| SCHEMBL3367827 | 0.76 | EGFR (0.49) | PDGFRBPDGFRAPARP1KMT2AALDH1A1 | |
| SCHEMBL9730933 | 0.75 | ALDH1A1 (0.49) | PDGFRBPDGFRAESR2KMT2AALDH1A1 | |
| Formamide SCHEMBL9731173 | 0.73 | PFKFB3 (0.40) | PDGFRBPDGFRAESR2KMT2AALDH1A1 | |
| SCHEMBL13544033 | 0.72 | ALDH1A1 (0.46) | PDGFRBPDGFRAPARP1KMT2AALDH1A1 | |
| SCHEMBL7938841 | 0.72 | HTT (0.46) | PDGFRBPDGFRAESR2PARP1KMT2A | |
| Formamide SCHEMBL9731189 | 0.72 | PFKFB3 (0.51) | PDGFRBPDGFRAESR2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |