Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2446728 | 1.00 | ESR2 (0.54) | ESR2PDGFRBPDGFRAALDH1A1KMT2A | |
| SCHEMBL15684790 | 0.86 | MAP4K4 (0.42) | ESR2PDGFRBPDGFRAKMT2AALDH5A1 | |
| SCHEMBL9797715 | 0.83 | PDGFRB (0.42) | PDGFRBPDGFRAALDH1A1KMT2ARAB9A | |
| Formamide SCHEMBL9730938 | 0.82 | PDGFRB (0.48) | ESR2PDGFRBPDGFRAALDH1A1KMT2A | |
| SCHEMBL9730933 | 0.81 | ALDH1A1 (0.49) | ESR2PDGFRBPDGFRAALDH1A1KMT2A | |
| SCHEMBL13510928 | 0.79 | PDGFRB (0.50) | PDGFRBPDGFRAALDH1A1RAB9AKDM4E | |
| SCHEMBL6769737 | 0.79 | EGFR (0.49) | PDGFRBPDGFRAALDH1A1KMT2AMEN1 | |
| SCHEMBL554880 | 0.79 | ALDH1A1 (0.50) | PDGFRBPDGFRAALDH1A1KMT2ARAB9A | |
| SCHEMBL15941521 | 0.79 | PDGFRB (0.47) | ESR2PDGFRBPDGFRAALDH1A1KMT2A | |
| SCHEMBL29953198 | 0.79 | RAB9A (0.47) | ESR2PDGFRBPDGFRAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |