Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731511 | 0.82 | MYC (0.37) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL9732739 | 0.78 | MGAM (0.51) | KMT2AKDM4ECYP1A2MGAMMAPT | |
| SCHEMBL9732925 | 0.78 | KMT2A (0.55) | KMT2AKDM4ECYP1A2MAPTMEN1 | |
| SCHEMBL9731610 | 0.75 | IDO1 (0.46) | KDM4ECYP1A2MAPTIDO1TDO2 | |
| SCHEMBL9731517 | 0.74 | IDO1 (0.38) | KDM4ECYP1A2MAPTIDO1TDO2 | |
| SCHEMBL5181112 | 0.74 | MGAM (0.58) | KMT2AKDM4EACHECYP1A2MGAM | |
| SCHEMBL9731190 | 0.73 | NQO2 (0.32) | KMT2AKDM4EMAPTMEN1LMNA | |
| SCHEMBL9731161 | 0.73 | ALDH1A1 (0.38) | KMT2AKDM4EMGAMMAPTMEN1 | |
| SCHEMBL9731179 | 0.72 | HSD17B14 (0.44) | KMT2AKDM4ECYP1A2MGAMMAPT | |
| SCHEMBL9731136 | 0.71 | ERN1 (0.40) | MGAMMAPTPOLBMAPK1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |