Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
| ▸ | ESRRB | O95718 | 1/20 | 0.33 |
| ▸ | ESRRA | P11474 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9732358 | 0.88 | ESR1 (0.36) | MEN1KMT2ALMNAESR1ESR2 | |
| SCHEMBL9730980 | 0.74 | EGFR (0.48) | MEN1KMT2ALMNAPOLBESR1 | |
| Formamide SCHEMBL9730946 | 0.73 | TLR8 (0.40) | MEN1KMT2ALMNAESR1ESR2 | |
| Formamide SCHEMBL9731312 | 0.71 | ESR2 (0.47) | MEN1KMT2ALMNAESR1ESR2 | |
| Formamide SCHEMBL9732767 | 0.71 | KDM4E (0.39) | MEN1KMT2ALMNANCOA3PARP1 | |
| Formamide SCHEMBL9731603 | 0.70 | MMP2 (0.39) | MEN1KMT2ALMNANCOA3PLAU | |
| SCHEMBL1204965 | 0.70 | ROCK1 (0.58) | MEN1KMT2ALMNAPOLBPLAU | |
| SCHEMBL2591464 | 0.69 | MEN1 (0.44) | MEN1KMT2ALMNAPOLBESR1 | |
| SCHEMBL30758878 | 0.69 | MEN1 (0.44) | MEN1KMT2ALMNAPOLBESR1 | |
| Formamide SCHEMBL9732590 | 0.69 | TRPM4 (0.35) | MEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122537-A | Tyrosine kinase inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-06-16 | — | — | US | disclosed |