Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730983 | 0.94 | HCAR2 (0.41) | MAOAMAOBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9731409 | 0.81 | NTRK2 (0.45) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6480081 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2999656 | 0.76 | MAOA (0.38) | MAOAMAOB | |
| SCHEMBL3004515 | 0.76 | MAOA (0.38) | MAOAMAOB | |
| SCHEMBL10458612 | 0.76 | KDM4E (0.55) | ALDH1A1L3MBTL1 | |
| SCHEMBL8611143 | 0.76 | KDM4E (0.55) | ALDH1A1L3MBTL1 | |
| SCHEMBL27917303 | 0.76 | KDM4E (0.57) | ALDH1A1MAPT | |
| SCHEMBL9731397 | 0.75 | NTRK2 (0.41) | — | |
| SCHEMBL368928 | 0.74 | KDM4E (0.55) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130317-A | Immunosuppressants and fibrosuppressants for metabolism of collagen | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |