Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10766120 | 0.76 | ALDH1A1 (0.43) | MAPTKDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL18193688 | 0.73 | MAPT (0.46) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL11600529 | 0.69 | MAPT (0.54) | MAPTKDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL9186785 | 0.69 | CYP1A2 (0.71) | MAPTKDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL18485267 | 0.67 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL6691525 | 0.67 | MAPT (0.55) | MAPTKDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL9731178 | 0.66 | MAPT (0.46) | MAPTKDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL6346878 | 0.63 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL14805661 | 0.63 | MAPT (0.46) | MAPTKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL8751989 | 0.62 | KDM4E (0.50) | MAPTKDM4EALDH1A1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162351-A | Nematocides | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| EP-0367365-A2 | Benzisothiazoles, process for their preparation and their use as pesticides | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-05-09 | — | — | EP | disclosed |