Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600529 | 0.83 | MAPT (0.54) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL18485267 | 0.79 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL9731178 | 0.75 | MAPT (0.46) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL18193688 | 0.75 | MAPT (0.46) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL14805661 | 0.75 | MAPT (0.46) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL10766120 | 0.72 | ALDH1A1 (0.43) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL290849 | 0.71 | KDM4E (1.00) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL29432549 | 0.71 | KDM4E (1.00) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL15665083 | 0.71 | MAPT (0.42) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL2954045 | 0.71 | MAPT (0.42) | MAPTKDM4EALDH1A1HSD17B10EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071740-A1 | ELASTOMERIC STRUCTURAL ELEMENTS | CROSSTIE TECHNOLOGIES, INC. (US) | 2004-08-26 | — | — | WO | claimed |
| WO-2004007606-A1 | RUBBER COMPOSITIONS AND METHODS FOR IMPROVING SCORCH SAFETY AND HYSTERETIC PROPERTIES OF THE COMPOSITIONS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2004-01-22 | — | — | WO | disclosed |