Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.45 |
| ▸ | CCR5 | P51681 | 3/20 | 0.45 |
| ▸ | CCR8 | P51685 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973168 | 0.85 | ADORA3 (0.49) | CCR1CCR5CCR8RAB9ASMN1; SMN2 | |
| SCHEMBL971029 | 0.85 | MEN1 (0.51) | SMN1; SMN2KDM4ELMNATSHRHSD17B10 | |
| SCHEMBL28190882 | 0.83 | KDM4E (0.58) | CCR1CCR5CCR8RAB9ASMN1; SMN2 | |
| SCHEMBL971520 | 0.82 | SMN1; SMN2 (0.48) | CCR1CCR5CCR8RAB9ASMN1; SMN2 | |
| SCHEMBL971571 | 0.82 | MAPK1 (0.48) | CCR1CCR5CCR8RAB9ASMN1; SMN2 | |
| SCHEMBL12579273 | 0.81 | DHODH (0.50) | RAB9ASMN1; SMN2NPC1TP53PKM | |
| SCHEMBL20954073 | 0.81 | KDM4E (0.54) | CCR1CCR5CCR8RAB9ASMN1; SMN2 | |
| SCHEMBL30757485 | 0.81 | KDM4E (0.54) | CCR1CCR5CCR8RAB9ASMN1; SMN2 | |
| SCHEMBL18623354 | 0.80 | KDM4E (0.51) | RAB9ASMN1; SMN2NPC1TP53PKM | |
| SCHEMBL10051241 | 0.80 | DHODH (0.49) | RAB9ASMN1; SMN2NPC1TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7867629-B2 | Nitrogenous heterocyclic derivative and organic electroluminescent element employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20060154105-A1 | Nitrogenous heterocyclic derivative and organic elecrtroluminescent element employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2006-07-13 | — | — | US | disclosed |
| EP-1582516-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2005-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154105-A1 | Nitrogenous heterocyclic derivative and organic elecrtroluminescent element employing the same | L1CAM, NOTCH1, NUDC | CCR1 4435/4885CCR5 4004/4885CCR8 3239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.