Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.65 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GNG2 | P59768 | 2/20 | 0.36 |
| ▸ | GNB1 | P62873 | 2/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588144 | 0.86 | NR4A2 (0.60) | NR4A2NCF1MAPTL3MBTL1KDM4E | |
| SCHEMBL439579 | 0.86 | NR4A2 (0.65) | NR4A2NCF1MAPTL3MBTL1KDM4E | |
| SCHEMBL9732129 | 0.83 | MAPT (0.61) | NR4A2MAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29410744 | 0.83 | MAPT (0.61) | NR4A2MAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL438980 | 0.79 | NR4A2 (1.00) | NR4A2NCF1MAPTL3MBTL1KDM4E | |
| SCHEMBL438225 | 0.76 | MCHR1 (0.42) | NR4A2MAPTPOLBLMNA | |
| SCHEMBL438259 | 0.74 | NR4A2 (0.54) | NR4A2NCF1MAPTKDM4ETDP1 | |
| SCHEMBL11557724 | 0.74 | NR4A2 (0.59) | NR4A2MAPTL3MBTL1KDM4ETDP1 | |
| SCHEMBL439448 | 0.74 | NR4A2 (0.59) | NR4A2NCF1MAPTL3MBTL1KDM4E | |
| SCHEMBL26535237 | 0.74 | CCR1 (0.58) | NR4A2NCF1MAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |