Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.41 |
| ▸ | HTR1D | P28221 | 6/20 | 0.37 |
| ▸ | HTR1B | P28222 | 6/20 | 0.37 |
| ▸ | HTR1F | P30939 | 6/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR1E | P28566 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731082 | 0.85 | ASAH1 (0.39) | ACKR3ASAH1HTR1DHTR1BHTR1F | |
| SCHEMBL9731662 | 0.84 | ACKR3 (0.39) | ACKR3ASAH1HTR1DHTR1BHTR1F | |
| Hydrochloric Acid SCHEMBL9731533 | 0.83 | ASAH1 (0.39) | ACKR3ASAH1HTR1DHTR1BHTR1F | |
| SCHEMBL9731074 | 0.81 | ACKR3 (0.38) | ACKR3ASAH1HTR1DHTR1BHTR1F | |
| Hydrochloric Acid SCHEMBL9731220 | 0.80 | ACKR3 (0.38) | ACKR3ASAH1HTR1DHTR1BHTR1F | |
| SCHEMBL10517962 | 0.77 | RBP4 (0.47) | ASAH1HTR1DHTR1BHTR1FHTR1A | |
| SCHEMBL9731774 | 0.75 | MAPK1 (0.37) | OPRL1 | |
| SCHEMBL9732619 | 0.75 | TRPV1 (0.35) | DRD2DRD3HTR2AKMT2A | |
| SCHEMBL4892167 | 0.75 | APP (0.45) | HTR1DHTR1BHTR1FOPRL1DRD2 | |
| SCHEMBL9732308 | 0.74 | ASAH1 (0.39) | ASAH1HTR1DHTR1BHTR1FOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081254-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1992-01-14 | — | — | US | claimed |
| EP-0374180-A1 | 4-QUINOLINE-3-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-06-27 | — | — | EP | claimed |
| WO-1989001933-A2 | 4-QUINOLINE-3-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1989-03-09 | — | — | WO | claimed |