Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | HTR1D | P28221 | 3/20 | 0.35 |
| ▸ | HTR1B | P28222 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | HTR1F | P30939 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731668 | 0.84 | HTR2A (0.38) | ASAH1ALDH1A1HTR2ATLR9TLR8 | |
| SCHEMBL10517969 | 0.77 | HTR6 (0.43) | ALDH1A1 | |
| SCHEMBL9731082 | 0.76 | ASAH1 (0.39) | ASAH1HTR1DHTR1BMAPTBLM | |
| Hydrochloric Acid SCHEMBL9731533 | 0.75 | ASAH1 (0.39) | ASAH1HTR1DHTR1BMAPTBLM | |
| SCHEMBL9731074 | 0.75 | ACKR3 (0.38) | ASAH1HTR1DHTR1BMAPTBLM | |
| SCHEMBL4892167 | 0.75 | APP (0.45) | HTR1DHTR1BTLR9TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL9731220 | 0.74 | ACKR3 (0.38) | ASAH1HTR1DHTR1BTLR9TLR8 | |
| SCHEMBL9732304 | 0.74 | ACKR3 (0.43) | ASAH1HTR2AHTR1DHTR1BMAPT | |
| SCHEMBL7007857 | 0.71 | HDAC1 (0.39) | ALDH1A1MAPT | |
| SCHEMBL30529258 | 0.71 | HDAC1 (0.39) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081254-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1992-01-14 | — | — | US | claimed |
| EP-0374180-A1 | 4-QUINOLINE-3-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1990-06-27 | — | — | EP | claimed |
| WO-1989001933-A2 | 4-QUINOLINE-3-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1989-03-09 | — | — | WO | claimed |