Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 3/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | CXCR4 | P61073 | 11/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297781 | 0.85 | KCNH2 (0.80) | KCNJ1KCNH2SIGMAR1 | |
| SCHEMBL31010199 | 0.84 | KCNJ1 (0.59) | KCNJ1KCNH2TDP1HRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2731720 | 0.84 | KCNH2 (0.78) | KCNJ1KCNH2SIGMAR1 | |
| SCHEMBL9733429 | 0.80 | KCNH2 (0.88) | KCNJ1KCNH2MEN1KMT2AHRH3 | |
| SCHEMBL31043120 | 0.79 | CXCR4 (0.54) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL1259387 | 0.73 | CXCR4 (0.81) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| Hydrochloric Acid SCHEMBL5573232 | 0.73 | CXCR4 (0.78) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL29339017 | 0.73 | SIGMAR1 (0.56) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL2710605 | 0.72 | ADRB1 (0.50) | SIGMAR1HTT | |
| SCHEMBL24694886 | 0.72 | HRH3 (0.47) | KCNH2CXCR4MEN1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112824-A | Benzofurazan compounds | MERCK & CO., INC. (US) | 1992-05-12 | — | — | US | disclosed |