Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.56 |
| ▸ | DRD4 | P21917 | 4/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18726569 | 0.87 | DRD4 (0.57) | SIGMAR1DRD4TMEM97DRD3DRD2 | |
| SCHEMBL19871856 | 0.84 | DRD4 (0.55) | SIGMAR1DRD4TMEM97DRD3DRD2 | |
| SCHEMBL29720511 | 0.84 | DRD4 (0.55) | SIGMAR1DRD4TMEM97DRD3PIK3CA | |
| SCHEMBL19869641 | 0.81 | DRD4 (0.55) | SIGMAR1DRD4TMEM97DRD3DRD2 | |
| SCHEMBL31043120 | 0.77 | CXCR4 (0.54) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL19567487 | 0.76 | DRD4 (0.47) | SIGMAR1DRD4TMEM97DRD3DRD2 | |
| SCHEMBL29363248 | 0.75 | DRD2 (0.61) | DRD2TDP1HRH3 | |
| SCHEMBL13974817 | 0.75 | TNIK (0.52) | SIGMAR1DRD4TMEM97DRD3DRD2 | |
| SCHEMBL29339022 | 0.74 | FGFR1 (0.56) | SIGMAR1CXCR4MEN1CHRM2CHRM1 | |
| SCHEMBL22001349 | 0.74 | IP6K1 (0.49) | SIGMAR1PIK3CADRD2HTR1AHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239780-A1 | MODIFIED FERROPORTIN INHIBITORS | VIFOR (INTERNATIONAL) AG (CH) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239780-A1 | MODIFIED FERROPORTIN INHIBITORS | SLC40A1, HAMP, TFRC | SIGMAR1 2688/4885DRD4 4388/4885TMEM97 721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.