Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.65 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 3/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | CMA1 | P23946 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.49 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.49 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19391 | 0.98 | AHR (0.67) | AHRPDE3BPDE3APGRPDK2 | |
| SCHEMBL31478025 | 0.82 | AHR (0.61) | AHRPDE3BPDE3APDK2MAOB | |
| SCHEMBL1833499 | 0.82 | AHR (0.61) | AHRPDE3BPDE3APDK2MAOB | |
| SCHEMBL426336 | 0.81 | NPC1 (0.55) | AHRPDE3BPDE3AMAOBMAOA | |
| SCHEMBL29853427 | 0.80 | TDP2 (0.51) | AHRPDK2MAOBMAOACMA1 | |
| SCHEMBL26768740 | 0.80 | TDP2 (0.51) | AHRPDK2MAOBMAOACMA1 | |
| SCHEMBL31734649 | 0.80 | MAOA (0.55) | AHRPDE3BPDE3APDK2MAOB | |
| SCHEMBL5639130 | 0.80 | AHR (0.50) | AHRPDE3BPDE3APGRPDK2 | |
| SCHEMBL154614 | 0.78 | AHR (1.00) | AHRPDE3BPDE3APGRPDK2 | |
| SCHEMBL6405990 | 0.78 | MAPT (0.58) | AHRMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007830-A2 | OXINDOLE PEPTIDE ANTAGONISTS | PFIZER INC. (US) | 1992-05-14 | — | — | WO | disclosed |