Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731265 | 0.92 | PRCP (0.44) | PRCPLMNAGAATP53HPGD | |
| SCHEMBL9732546 | 0.71 | CA1 (0.39) | SIGMAR1DRD1 | |
| SCHEMBL1143328 | 0.69 | GAA (0.59) | PRCPLMNAGAATP53HPGD | |
| SCHEMBL9732352 | 0.65 | INMT (0.47) | LMNASIGMAR1DRD1 | |
| SCHEMBL9730970 | 0.64 | PRCP (0.46) | PRCPLMNAGAATP53HPGD | |
| SCHEMBL1722733 | 0.62 | GAA (0.51) | PRCPLMNAGAATP53HPGD | |
| SCHEMBL6860623 | 0.61 | HSD11B1 (0.43) | LMNA | |
| SCHEMBL11166800 | 0.61 | SLC6A2 (0.53) | PRCPLMNASIGMAR1DRD1 | |
| SCHEMBL809801 | 0.60 | STAT3 (0.38) | — | |
| SCHEMBL9629222 | 0.60 | PRCP (0.51) | PRCPHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106844-A | Imidazo[2,2-b][3]benzazepine and pyrimido[2,1-b][3]benzazepine antiarrhythmic agents | STERLING DRUG INC. (US) | 1992-04-21 | — | — | US | claimed |
| US-5106844-A | Imidazo[2,2-b][3]benzazepine and pyrimido[2,1-b][3]benzazepine antiarrhythmic agents | STERLING DRUG INC. (US) | 1992-04-21 | — | — | US | disclosed |