Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731147 | 0.85 | ALOX12 (0.47) | PRCPGAAALOX12DRD1P2RX7 | |
| SCHEMBL1143328 | 0.69 | GAA (0.59) | PRCPGAALMNATP53HPGD | |
| SCHEMBL17595643 | 0.68 | KDM4E (0.43) | PRCPGAAP2RX7 | |
| SCHEMBL13185710 | 0.66 | KMT2A (0.40) | LMNATP53HPGDDRD1SIGMAR1 | |
| SCHEMBL9731265 | 0.66 | PRCP (0.44) | PRCPGAALMNATP53HPGD | |
| SCHEMBL7142797 | 0.65 | DRD1 (0.48) | LMNAHPGDDRD1 | |
| SCHEMBL21239650 | 0.64 | P2RX7 (0.47) | PRCPP2RX7 | |
| SCHEMBL17596490 | 0.64 | P2RX7 (0.60) | P2RX7 | |
| SCHEMBL9733116 | 0.64 | PRCP (0.42) | PRCPGAALMNATP53HPGD | |
| SCHEMBL13928812 | 0.63 | PRCP (1.00) | PRCPDRD1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106844-A | Imidazo[2,2-b][3]benzazepine and pyrimido[2,1-b][3]benzazepine antiarrhythmic agents | STERLING DRUG INC. (US) | 1992-04-21 | — | — | US | disclosed |