Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.66 |
| ▸ | HTR6 | P50406 | 2/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732896 | 0.98 | PLA2G2A (0.69) | PLA2G2AHTR6MTNR1AMTNR1BLMNA | |
| SCHEMBL9732645 | 0.91 | PLA2G2A (0.61) | PLA2G2AHTR6MTNR1AMTNR1BLMNA | |
| SCHEMBL9731962 | 0.89 | PLA2G2A (0.61) | PLA2G2AHTR6MTNR1AMTNR1BLMNA | |
| SCHEMBL9732531 | 0.88 | PLA2G2A (0.55) | PLA2G2AHTR6MTNR1AMTNR1BLMNA | |
| SCHEMBL9733154 | 0.86 | PLA2G2A (0.50) | PLA2G2AHTR6MTNR1AMTNR1BPPARG | |
| SCHEMBL9733190 | 0.85 | PLA2G2A (0.60) | PLA2G2AHTR6MTNR1AMTNR1BLMNA | |
| SCHEMBL9732684 | 0.85 | PLA2G2A (0.59) | PLA2G2AHTR6MTNR1AMTNR1BLMNA | |
| SCHEMBL9732157 | 0.85 | PLA2G2A (0.49) | PLA2G2AHTR6MTNR1AMTNR1BLMNA | |
| Hydrochloric Acid SCHEMBL9733235 | 0.85 | PLA2G2A (0.59) | PLA2G2AHTR6MTNR1AMTNR1BLMNA | |
| SCHEMBL12083183 | 0.83 | PLA2G2A (0.74) | PLA2G2AHTR6MTNR1AMTNR1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | claimed |
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |