Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732157 | 0.89 | PLA2G2A (0.49) | PLA2G2AHTR6MTNR1AMTNR1BCHRNB2 | |
| SCHEMBL9733129 | 0.86 | PLA2G2A (0.66) | PLA2G2AHTR6MTNR1AMTNR1BCHRNB2 | |
| SCHEMBL9732896 | 0.83 | PLA2G2A (0.69) | PLA2G2AHTR6MTNR1AMTNR1BCHRNB2 | |
| SCHEMBL9732518 | 0.83 | ICMT (0.48) | PLA2G2AHTR6KDM4EP2RX7 | |
| SCHEMBL9731962 | 0.78 | PLA2G2A (0.61) | PLA2G2AHTR6MTNR1AMTNR1BTP53 | |
| SCHEMBL9732645 | 0.78 | PLA2G2A (0.61) | PLA2G2AHTR6MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL9734393 | 0.77 | MAPT (0.51) | PLA2G2AMTNR1AMTNR1BTP53SMN1; SMN2 | |
| SCHEMBL1609182 | 0.77 | HDAC6 (0.59) | PLA2G2AMTNR1AMTNR1B | |
| SCHEMBL4251198 | 0.77 | HDAC6 (0.47) | PLA2G2AHTR6MTNR1AMTNR1BCHRNB2 | |
| SCHEMBL9732159 | 0.77 | KDM4E (0.48) | PLA2G2AHTR6TP53KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |