Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9733258 | 0.99 | USP2 (0.39) | USP2SMN1; SMN2KDM1ACYP1A2CYP2D6 | |
| SCHEMBL9732994 | 0.85 | NPC1 (0.46) | USP2SMN1; SMN2TP53TSHR | |
| Hydrochloric Acid SCHEMBL9733674 | 0.84 | NPC1 (0.46) | USP2SMN1; SMN2TP53TSHR | |
| SCHEMBL9696959 | 0.82 | TSHR (0.47) | USP2SMN1; SMN2KDM1ACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL9697582 | 0.81 | TSHR (0.46) | USP2SMN1; SMN2KDM1ACYP1A2CYP2D6 | |
| SCHEMBL3360368 | 0.80 | TSHR (0.48) | USP2SMN1; SMN2KDM1ACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL9697076 | 0.79 | TSHR (0.47) | USP2SMN1; SMN2KDM1ACYP1A2CYP2D6 | |
| SCHEMBL9696030 | 0.78 | TNKS (0.42) | USP2SMN1; SMN2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9753089 | 0.75 | SMN1; SMN2 (0.49) | USP2SMN1; SMN2HDAC1TSHRHDAC6 | |
| SCHEMBL9753017 | 0.74 | TSHR (0.45) | USP2SMN1; SMN2CASP1HDAC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104892-A | N-heteroalkyl substitutes 1-aryloxy-2-propanolamine | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-04-14 | — | — | US | claimed |
| US-5104892-A | N-heteroalkyl substitutes 1-aryloxy-2-propanolamine | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-04-14 | — | — | US | disclosed |