SCHEMBL9733206

SCHEMBL9733206

N#CC1CC2(CCCCC2)CN1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CTSC P53634 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5009996 0.67
SCHEMBL8354161 0.67
SCHEMBL24069665 0.67 ALPL (0.38)
SCHEMBL9000263 0.67 ALPL (0.38)
SCHEMBL17450395 0.67 ALPL (0.38)
SCHEMBL13741815 0.66 ALDH1A1 (0.35)
SCHEMBL13742501 0.66 ALDH1A1 (0.35)
Hydrochloric Acid SCHEMBL3848539 0.65
SCHEMBL15296978 0.64 ALPL (0.39)
SCHEMBL18019413 0.64 ALPL (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5175306-A Intermediates for hypotensive agents HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-29 US disclosed
US-4822894-A PURE CIS ENANTIOMERS OF FUSED PYRROLE RING CARBOXYLATES HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-18 US disclosed
EP-0094633-B1 SPIRO-2-AZA-ALKANE-3-CARBONITRILES, PROCESS FOR THEIR PREPARATION AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-09 EP disclosed
EP-0115345-B1 PROCESS FOR THE RESOLUTION OF RACEMIC OPTICALLY ACTIVE BICYCLIC IMINO-ALPHA-CARBOXYLIC ACID ESTERS AND USE OF THE COMPOUNDS OBTAINABLE IN THIS WAY FOR THE SYNTHESIS OF CARBOXYALKYL DIPEPTIDES HOECHST AKTIENGESELLSCHAFT (DE) 1988-01-07 EP disclosed
US-4668796-A Racemates of optically active bicyclic imino-alpha-carboxylic esters HOECHST AKTIENGESELLSCHAFT (DE) 1987-05-26 US disclosed
EP-0034015-B1 PHARMACEUTICALLY ACTIVE COMPOUNDS BEECHAM GROUP PLC (GB) 1986-03-26 EP disclosed
EP-0115345-A1 Process for the resolution of racemic optically active bicyclic imino-alpha-carboxylic acid esters and use of the compounds obtainable in this way for the synthesis of carboxyalkyl dipeptides HOECHST AKTIENGESELLSCHAFT (DE) 1984-08-08 EP disclosed
EP-0094633-A2 Spiro-2-aza-alkane-3-carbonitriles, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1983-11-23 EP disclosed