Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732650 | 0.85 | ICMT (0.45) | HTR6PARP1ICMTALDH1A1APP | |
| SCHEMBL9733190 | 0.85 | PLA2G2A (0.60) | HTR6ICMTALDH1A1LMNAKMT2A | |
| SCHEMBL9733098 | 0.85 | ICMT (0.50) | ICMT | |
| Hydrochloric Acid SCHEMBL9733090 | 0.85 | ICMT (0.44) | HTR6ICMTALDH1A1APPLMNA | |
| Hydrochloric Acid SCHEMBL9733235 | 0.85 | PLA2G2A (0.59) | HTR6ICMTALDH1A1LMNAKMT2A | |
| SCHEMBL9734463 | 0.84 | RXFP1 (0.46) | POLBICMTAPPMAPT | |
| SCHEMBL9731969 | 0.84 | ICMT (0.50) | ICMTALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL9732261 | 0.84 | ICMT (0.56) | HTR6ICMTADAM17 | |
| SCHEMBL30389137 | 0.84 | HTR2C (0.59) | HTR6HTR2CCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL9585816 | 0.82 | ICMT (0.56) | ICMTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |