Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | CASR | P41180 | 7/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732947 | 0.89 | PLA2G2A (0.62) | PLA2G2AHTR6MTNR1AMTNR1BCASR | |
| SCHEMBL9732883 | 0.89 | PLA2G2A (0.62) | PLA2G2AHTR6MTNR1AMTNR1BCASR | |
| SCHEMBL10380958 | 0.88 | PLA2G2A (0.59) | PLA2G2AHTR6MTNR1AMTNR1BADRB2 | |
| SCHEMBL9733190 | 0.84 | PLA2G2A (0.60) | PLA2G2AHTR6MTNR1AMTNR1BADRB2 | |
| Hydrochloric Acid SCHEMBL9733235 | 0.83 | PLA2G2A (0.59) | PLA2G2AHTR6MTNR1AMTNR1BADRB2 | |
| SCHEMBL9732645 | 0.79 | PLA2G2A (0.61) | PLA2G2AHTR6MTNR1AMTNR1BADRB2 | |
| SCHEMBL9733982 | 0.78 | PLA2G2A (0.62) | PLA2G2AHTR6MTNR1AMTNR1BICMT | |
| SCHEMBL10443452 | 0.78 | PLA2G2A (0.67) | PLA2G2AHTR6MTNR1AMTNR1BICMT | |
| SCHEMBL9585417 | 0.78 | PLA2G2A (0.67) | PLA2G2AHTR6MTNR1AMTNR1BICMT | |
| SCHEMBL9585680 | 0.78 | PLA2G2A (0.67) | PLA2G2AHTR6MTNR1AMTNR1BICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007829-A1 | INDOLE-3-METHANAMINES USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |