Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733529 | 0.82 | ABCC9 (0.41) | ABCC9CNR2ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9733792 | 0.82 | CNR2 (0.37) | ABCC9CNR2ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7331710 | 0.80 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9734651 | 0.74 | CNR2 (0.38) | ABCC9CNR2ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9733302 | 0.73 | ABCC9 (0.38) | ABCC9CNR2ABCC8KCNJ11KCNJ8 | |
| SCHEMBL1573018 | 0.73 | CYP11B1 (0.49) | ABCC9CNR2ABCC8KCNJ11KCNJ8 | |
| SCHEMBL10560535 | 0.72 | CNR2 (0.42) | ABCC9CNR2ABCC8KCNJ11KCNJ8 | |
| SCHEMBL10560531 | 0.72 | CNR2 (0.42) | ABCC9CNR2ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7333125 | 0.71 | ABCC9 (0.56) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7269481 | 0.71 | ABCC9 (0.56) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132307-A | TETRALIN COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-21 | — | — | US | disclosed |