SCHEMBL9733542

SCHEMBL9733542

CC1(C)CCC=C(C(=O)c2ccc(S(C)(=O)=O)cc2[N+](=O)[O-])C1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.39
ALDH3A1 P30838 4/20 0.38
MAPT P10636 4/20 0.36
LMNA P02545 2/20 0.36
GAA P10253 1/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
RAB9A P51151 3/20 0.36
HTT P42858 2/20 0.36
MAPK1 P28482 2/20 0.36
NPC1 O15118 2/20 0.36
MITF O75030 1/20 0.36
CCR6 P51684 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
KDM4E B2RXH2 1/20 0.35
RXRA P19793 1/20 0.34
FLT1 P17948 2/20 0.33
FLT4 P35916 2/20 0.33
KDR P35968 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9733127 0.78 ALDH1A1 (0.40) ALDH1A1ALDH3A1MAPTLMNAGAA
SCHEMBL909773 0.71 HPD (0.45) ALDH1A1ALDH3A1MAPTLMNAGAA
Hydrogen Peroxide SCHEMBL28991385 0.71 ALDH1A1 (0.56) ALDH1A1ALDH3A1MAPTLMNAGAA
SCHEMBL18287474 0.71 ALDH3A1 (0.53) ALDH1A1ALDH3A1MAPTLMNAGAA
SCHEMBL1202449 0.71 ALDH1A1 (0.56) ALDH1A1ALDH3A1MAPTLMNAGAA
SCHEMBL27716980 0.71 ALDH1A1 (0.52) ALDH1A1ALDH3A1MAPTLMNAGAA
SCHEMBL28848206 0.70 ALDH1A1 (0.40) ALDH1A1ALDH3A1MAPTLMNAGAA
SCHEMBL2084156 0.70 ALDH1A1 (0.51) ALDH1A1ALDH3A1MAPTLMNAGAA
SCHEMBL30595897 0.70 ALDH1A1 (0.51) ALDH1A1ALDH3A1MAPTLMNAGAA
Lithium Ion SCHEMBL29035600 0.70 ALDH1A1 (0.51) ALDH1A1ALDH3A1MAPTLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5152826-A Herbicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-10-06 US disclosed