Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10806978 | 0.79 | PIN1 (0.41) | CHRM2CHRM1CHRM3CHRM4ESR1 | |
| SCHEMBL7450936 | 0.78 | TSHR (0.42) | CHRM2CHRM1CHRM3CHRM4ESR1 | |
| SCHEMBL22119058 | 0.77 | PIN1 (0.45) | CHRM2CHRM1CHRM3CHRM4TSHR | |
| SCHEMBL1456077 | 0.75 | ALDH1A1 (0.43) | CHRM2CHRM1CHRM3CHRM4ESR1 | |
| SCHEMBL2289504 | 0.75 | CHRM3 (0.46) | CHRM2CHRM1CHRM3CHRM4TSHR | |
| SCHEMBL2989486 | 0.75 | TSHR (0.42) | CHRM2CHRM1CHRM3CHRM4ESR1 | |
| SCHEMBL2997460 | 0.74 | ESR1 (0.46) | CHRM2CHRM1CHRM3CHRM4ESR1 | |
| SCHEMBL3458134 | 0.74 | PIN1 (0.42) | CHRM2CHRM1CHRM3CHRM4ESR1 | |
| SCHEMBL11024141 | 0.74 | TSHR (0.41) | CHRM2CHRM1CHRM3CHRM4ESR1 | |
| SCHEMBL6136786 | 0.74 | ALDH1A1 (0.42) | CHRM2CHRM1CHRM3CHRM4ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164386-A | Gastrointestinal and respiratory disorders | ISTITUTO DE ANGELI S.P.A. (IT) | 1992-11-17 | — | — | US | disclosed |
| EP-0404737-A2 | New R(-) 3-quinuclidinol derivatives | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1990-12-27 | — | — | EP | disclosed |