Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27575627 | 0.87 | TSHR (0.44) | ALDH1A1KDM4EGAALMNAHTT | |
| SCHEMBL13069739 | 0.83 | TSHR (0.48) | KDM4ELMNAHTTPOLBNPSR1 | |
| SCHEMBL1456077 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAALMNAHTT | |
| SCHEMBL2989486 | 0.82 | TSHR (0.42) | ALDH1A1KDM4EGAALMNAHTT | |
| SCHEMBL7450936 | 0.82 | TSHR (0.42) | ALDH1A1KDM4EGAALMNAHTT | |
| SCHEMBL2289504 | 0.82 | CHRM3 (0.46) | ALDH1A1KDM4EGAAPOLBTSHR | |
| SCHEMBL2997460 | 0.81 | ESR1 (0.46) | ALDH1A1KDM4EGAALMNAHTT | |
| SCHEMBL2130216 | 0.81 | PIN1 (0.44) | ALDH1A1KDM4EGAALMNAHTT | |
| SCHEMBL11024141 | 0.81 | TSHR (0.41) | ALDH1A1KDM4EGAAPOLBNPSR1 | |
| SCHEMBL10335551 | 0.79 | CHRM3 (0.47) | ALDH1A1KDM4EGAATSHRPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337218-A4 | SUBSTITUTED FELBAMATE DERIVED COMPOUNDS | UNIV VIRGINIA (US) | 2005-08-10 | — | — | EP | disclosed |
| US-20040023986-A1 | Substituted felbamate derived compounds | GENERAL ELECTRIC CAPITAL CORPORATION | 2004-02-05 | — | — | US | disclosed |
| EP-1337218-A2 | SUBSTITUTED FELBAMATE DERIVED COMPOUNDS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002056827-A2 | SUBSTITUTED FELBAMATE DERIVED COMPOUNDS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2002-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023986-A1 | Substituted felbamate derived compounds | CACNA1B, GABRB1, GABRB3 | ALDH1A1 485/4885KDM4E 1697/4885GAA 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.