Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 11/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22569218 | 0.86 | GGPS1 (0.41) | TSHRFDPSGGPS1CES2 | |
| SCHEMBL28433028 | 0.86 | GGPS1 (0.41) | TSHRFDPSGGPS1CES2 | |
| SCHEMBL18124683 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL18124692 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL8028876 | 0.83 | SMN1; SMN2 (0.33) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL31544641 | 0.81 | LMNA (0.34) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL9232200 | 0.81 | SMN1; SMN2 (0.32) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL8032433 | 0.81 | LMNA (0.36) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9237557 | 0.79 | LMNA (0.34) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL23627348 | 0.78 | LMNA (0.40) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5157029-A | Insecticides, miticides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-10-20 | — | — | US | disclosed |