Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.35 |
| ▸ | FDPS | P14324 | 9/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028876 | 0.98 | SMN1; SMN2 (0.33) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8034779 | 0.92 | TSHR (0.32) | ALDH1A1TSHR | |
| SCHEMBL8029070 | 0.83 | TSHR (0.35) | TSHR | |
| SCHEMBL9237557 | 0.82 | LMNA (0.34) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9733658 | 0.81 | SMN1; SMN2 (0.36) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9232200 | 0.80 | SMN1; SMN2 (0.32) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8034767 | 0.80 | LMNA (0.36) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8030677 | 0.80 | LMNA (0.36) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL15326277 | 0.79 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL18124692 | 0.79 | SMN1; SMN2 (0.38) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635512-B1 | Cyclic phosphites as polymer stabilizers | GEN ELECTRIC (US) | 2000-03-01 | — | — | EP | disclosed |
| US-5464889-A | Stabilization of thermoplastic resins | GENERAL ELECTRIC COMPANY (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0635512-A1 | Cyclic phosphites as polymer stabilizers | GENERAL ELECTRIC COMPANY (US) | 1995-01-25 | — | — | EP | disclosed |