SCHEMBL8028876

SCHEMBL8028876

CCCCCC(C)(CO)C(O)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.33
FDPS P14324 10/20 0.32
GGPS1 O95749 7/20 0.32
LMNA P02545 3/20 0.32
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8032433 0.98 LMNA (0.36) FDPSGGPS1LMNATSHRALDH1A1
SCHEMBL8034779 0.94 TSHR (0.32) TSHRALDH1A1
SCHEMBL8029070 0.85 TSHR (0.35) TSHR
SCHEMBL9733658 0.83 SMN1; SMN2 (0.36) SMN1; SMN2FDPSGGPS1LMNATSHR
SCHEMBL9232200 0.82 SMN1; SMN2 (0.32) SMN1; SMN2FDPSGGPS1LMNATSHR
SCHEMBL15326277 0.81 ALDH1A1 (0.31) ALDH1A1
SCHEMBL18124683 0.80 SMN1; SMN2 (0.38) SMN1; SMN2FDPSGGPS1LMNATSHR
SCHEMBL18124692 0.80 SMN1; SMN2 (0.38) SMN1; SMN2FDPSGGPS1LMNATSHR
SCHEMBL9237557 0.80 LMNA (0.34) FDPSGGPS1LMNATSHRALDH1A1
SCHEMBL31544641 0.78 LMNA (0.34) SMN1; SMN2FDPSGGPS1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0635512-B1 Cyclic phosphites as polymer stabilizers GEN ELECTRIC (US) 2000-03-01 EP disclosed
US-5464889-A Stabilization of thermoplastic resins GENERAL ELECTRIC COMPANY (US) 1995-11-07 US disclosed
EP-0635512-A1 Cyclic phosphites as polymer stabilizers GENERAL ELECTRIC COMPANY (US) 1995-01-25 EP disclosed