Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254528 | 0.96 | ALDH1A1 (0.56) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| Hydrogen Peroxide SCHEMBL28470548 | 0.91 | ALDH1A1 (0.55) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| SCHEMBL10915895 | 0.84 | POLB (0.58) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| SCHEMBL9335500 | 0.84 | HSPB1 (0.59) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| SCHEMBL2419682 | 0.84 | MAPT (0.65) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| SCHEMBL4687553 | 0.83 | ALDH1A1 (0.72) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| SCHEMBL2684005 | 0.83 | SRD5A2 (0.62) | ALDH1A1MAPTTSHRMAPK1TDP1 | |
| SCHEMBL353942 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| SCHEMBL811522 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| SCHEMBL352795 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ACHEMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079248-A | Antifibrillatory agents; side effect reduction | PFIZER INC. (US) | 1992-01-07 | — | — | US | disclosed |
| US-4959366-A | Anti-arrhythmic agents | PFIZER INC. (US) | 1990-09-25 | — | — | US | disclosed |