Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353942 | 1.00 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| SCHEMBL811522 | 1.00 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| Hydrochloric Acid SCHEMBL248092 | 0.98 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| Hydrochloric Acid SCHEMBL913942 | 0.98 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| Hydrochloric Acid SCHEMBL913941 | 0.98 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| Ammonia Solution, Strong SCHEMBL4826153 | 0.98 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| SCHEMBL30913865 | 0.94 | CA12 (0.53) | ALDH1A1HSD17B10ACHEMAPTTSHR | |
| SCHEMBL20303794 | 0.89 | L3MBTL1 (0.58) | ALDH1A1HSD17B10MAPTTSHRMAPK1 | |
| SCHEMBL21774543 | 0.89 | L3MBTL1 (0.58) | ALDH1A1HSD17B10MAPTTSHRMAPK1 | |
| SCHEMBL11813645 | 0.88 | LOXL2 (0.70) | ALDH1A1HSD17B10ACHEMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119035-A | RIPK1 kinase target inhibitor and preparation method and application thereof | 中山大学 | 2024-12-13 | — | — | CN | claimed |
| CN-118084733-A | Preparation method of key intermediate for synthesizing tubulin inhibitor | 重庆皓元生物制药有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-1705639-A | Synthesis of intermediates useful in the synthesis of tubulin inhibitors | WYETH CORP (US) | 2005-12-07 | — | — | CN | claimed |
| US-6951955-B2 | Process for the synthesis of intermediates useful for the synthesis of tubulin inhibitors | WYETH HOLDINGS CORPORATION (US) | 2005-10-04 | — | — | US | claimed |
| EP-1539682-A2 | PROCESS FOR THE SYNTHESIS OF INTERMEDIATES USEFUL FOR THE SYNTHESIS OF TUBULIN INHIBITORS | Wyeth Holdings Corporation (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2004026814-A2 | PROCESS FOR THE SYNTHESIS OF INTERMEDIATES USEFUL FOR THE SYNTHESIS OF TUBULIN INHIBITORS | WYETH HOLDINGS CORPORATION (US) | 2004-04-01 | — | — | WO | claimed |
| US-20040063904-A1 | Process for the synthesis of intermediates useful for the synthesis of tubulin inhibitors | WYETH HOLDINGS CORPORATION | 2004-04-01 | — | — | US | claimed |
| EP-0618213-B1 | Process for preparation of oxyglutaric acid ester derivatives | UBE INDUSTRIES (JP) | 2000-05-17 | — | — | EP | claimed |
| US-5717124-A | Process for preparation of oxyglutaric acid ester derivatives | UBE INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | claimed |
| EP-0618213-A1 | Process for preparation of oxyglutaric acid ester derivatives | UBE INDUSTRIES, LTD. (JP) | 1994-10-05 | — | — | EP | claimed |
| US-4066658-A | RESOLUTION OF D,L-DEHYDROPROLINE | HOFFMANN-LA ROCHE INC. (US) | 1978-01-03 | — | — | US | claimed |
| US-3988349-A | Salts of N-formyl-6-chlorotryptophan and α-methyl-p-nitrobenzylamine | HOFFMANN-LA ROCHE INC. (US) | 1976-10-26 | — | — | US | claimed |
| JP-6192277-A | — | — | None | — | — | JP | disclosed |
| US-12465588-B2 | Indole carboxamide derivative and pharmaceutical composition containing same | KUKJE PHARMA CO., LTD. (KR) | 2025-11-11 | — | — | US | disclosed |
| US-20250115600-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. | 2025-04-10 | — | — | US | disclosed |
| CN-114302874-B | Indole carboxamide derivatives and pharmaceutical compositions containing the same | 国际药品株式会社 | 2025-02-25 | — | — | CN | disclosed |
| US-4066658-A | RESOLUTION OF D,L-DEHYDROPROLINE | HOFFMANN-LA ROCHE INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-3988349-A | Salts of N-formyl-6-chlorotryptophan and α-methyl-p-nitrobenzylamine | HOFFMANN-LA ROCHE INC. (US) | 1976-10-26 | — | — | US | disclosed |
| US-3965121-A | Salts of the γ-lactone of (-)-threo-hydroxycitric acid with R(+)-α-methyl-p-nitrobenzylamine | HOFFMANN-LA ROCHE INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3965129-A | THREO-EPOXYACONITIC ACID BIS-R(+)-ALPHA-METHYL-P-NITROBENZYLAMINE SALT | HOFFMANN-LA ROCHE INC. (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12465588-B2 | Indole carboxamide derivative and pharmaceutical composition containing same | PTGES, PTGES2, PTGS1 | ALDH1A1 331/4885HSD17B10 742/4885ACHE 31/4885 |
| US-20250115600-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | AKT1, AKT1S1, AKT2 | ALDH1A1 4472/4885HSD17B10 2922/4885ACHE 3854/4885 |
| US-20040063904-A1 | Process for the synthesis of intermediates useful for the synthesis of tubulin inhibitors | TUBB1, TUBA1C, TUBB | ALDH1A1 787/4885HSD17B10 1602/4885ACHE 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.