Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 6/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738782 | 0.79 | CNR2 (0.37) | ABCC9CNR2ABCB1CYP11B1CYP11B2 | |
| SCHEMBL9735224 | 0.78 | BACE1 (0.36) | ABCC9CNR2ABCB1 | |
| SCHEMBL7332132 | 0.78 | ABCC9 (0.56) | ABCC9ABCB1 | |
| SCHEMBL9733529 | 0.77 | ABCC9 (0.41) | ABCC9CNR2HCRTR2ABCB1 | |
| SCHEMBL1573018 | 0.72 | CYP11B1 (0.49) | ABCC9CNR2ABCB1CYP11B1CYP11B2 | |
| SCHEMBL10560531 | 0.72 | CNR2 (0.42) | ABCC9CNR2ABCB1CYP11B1CYP11B2 | |
| SCHEMBL10560535 | 0.72 | CNR2 (0.42) | ABCC9CNR2ABCB1CYP11B1CYP11B2 | |
| SCHEMBL9735072 | 0.71 | ABCC9 (0.36) | ABCC9CNR2ABCB1CYP11B1CYP11B2 | |
| SCHEMBL8076948 | 0.70 | ABCC9 (0.43) | ABCC9ABCB1 | |
| SCHEMBL10564738 | 0.69 | CNR2 (0.48) | ABCC9CNR2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132307-A | TETRALIN COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-21 | — | — | US | disclosed |
| EP-0368160-A1 | Tetralin derivatives | MERCK PATENT GmbH (DE) | 1990-05-16 | — | — | EP | disclosed |