Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | SDHB | P21912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123322 | 0.86 | KDM4E (0.53) | HTTMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL30813138 | 0.86 | KDM4E (0.53) | HTTMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL13312285 | 0.85 | MGLL (0.44) | HTTMGLLALDH1A1KDM4EKMT2A | |
| SCHEMBL3433408 | 0.84 | MGLL (0.43) | HTTMGLLALDH1A1KDM4ETDP1 | |
| SCHEMBL11909549 | 0.84 | LMNA (0.50) | MGLLALDH1A1KDM4ETDP1GAA | |
| SCHEMBL125418 | 0.83 | KDM4E (0.47) | ALOX15HTTMAPTMGLLALDH1A1 | |
| SCHEMBL2192041 | 0.82 | MGLL (0.40) | ALOX15HTTMGLLKDM4EKMT2A | |
| SCHEMBL30440154 | 0.82 | MGLL (0.40) | ALOX15HTTMGLLKDM4EKMT2A | |
| SCHEMBL5717652 | 0.82 | PARP1 (0.46) | HTTMAPTMGLLKDM4EKMT2A | |
| SCHEMBL123859 | 0.82 | MGLL (0.42) | HTTMGLLALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102006777-B | Herbicidal compounds | SYNGENTA LTD | 2015-04-01 | — | — | CN | disclosed |
| US-8461083-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2013-06-11 | — | — | US | disclosed |
| CN-102006777-A | Herbicidal coumpounds | SYNGENTA LTD | 2011-04-06 | — | — | CN | disclosed |
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021352-A1 | HERBICIDAL COMPOUNDS | RDX, NQO2, DDT | ALOX15 4339/4885HTT 930/4885MAPT 4399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.