Valine

SCHEMBL9734133

CC(C)[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)O.CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)O.NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN)C(=O)[O-].NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN)C(=O)[O-].[Cu+2]

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	SLC15A2	Q16348	1/20	0.42

▸	OPRK1	P41145	2/20	0.40

▸	GHSR	Q92847	6/20	0.39

▸	PSMB1	P20618	1/20	0.39

▸	PSMB8	P28062	1/20	0.39

▸	PSMB9	P28065	1/20	0.39

▸	PSMB5	P28074	1/20	0.39

▸	PSMB10	P40306	1/20	0.39

▸	PSMB2	P49721	1/20	0.39

▸	C5AR1	P21730	2/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Valine SCHEMBL9734140	0.94	SLC15A2 (0.45)	SLC15A2OPRK1GHSRPSMB1PSMB8
SCHEMBL5970308	0.87	GHSR (0.47)	OPRK1GHSRPSMB1PSMB8PSMB9
SCHEMBL9389399	0.86	SLC15A2 (0.46)	SLC15A2GHSRC5AR1
SCHEMBL9747695	0.86	SLC15A2 (0.46)	SLC15A2GHSRC5AR1
SCHEMBL6382012	0.86	SLC15A2 (0.46)	SLC15A2GHSRC5AR1
SCHEMBL5527046	0.86	GHSR (0.44)	SLC15A2GHSRC5AR1
SCHEMBL10625459	0.85	SLC15A2 (0.45)	SLC15A2GHSRC5AR1
SCHEMBL4589605	0.85	GHSR (0.47)	OPRK1GHSRPSMB1PSMB8PSMB9
SCHEMBL9614994	0.85	GHSR (0.41)	SLC15A2OPRK1GHSRC5AR1
SCHEMBL9751592	0.84	OPRK1 (0.45)	OPRK1GHSRPSMB1PSMB8PSMB9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5164367-A	Complexes with peptides	PROCYTE CORPORATION (US)	1992-11-17	—	—	US	disclosed