Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | DHPS | P49366 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28494045 | 0.76 | KMT2A (0.55) | HTR2CMAPK1PDE2ADHPSLTA4H | |
| SCHEMBL30215796 | 0.76 | PDE2A (0.71) | HTR2CMAPK1PDE2ADHPSLTA4H | |
| SCHEMBL28428180 | 0.75 | HTT (0.56) | MEN1KMT2AL3MBTL1POLBNPSR1 | |
| SCHEMBL29162739 | 0.75 | MPO (0.46) | HTR2CDHPSLTA4HALDH1A1CYP1A2 | |
| SCHEMBL2614741 | 0.75 | CALM1 (0.61) | MAPK1PDE2AMEN1KMT2AL3MBTL1 | |
| SCHEMBL28647099 | 0.71 | PDE2A (0.47) | HTR2CMAPK1PDE2ADHPSLTA4H | |
| SCHEMBL11194000 | 0.70 | PDE2A (0.46) | HTR2CMAPK1PDE2ADHPSLTA4H | |
| SCHEMBL1622308 | 0.70 | HTR2C (0.64) | HTR2CMAPK1MEN1KMT2A | |
| SCHEMBL14163912 | 0.70 | TP53 (0.50) | HTR2CMAPK1PDE2AMEN1KMT2A | |
| SCHEMBL17358224 | 0.70 | L3MBTL1 (0.49) | MAPK1PDE2AMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119951591-A | Preparation method of composite photocatalytic material for degrading trimethoprim sewage | 北方工业大学 | 2025-05-09 | — | — | CN | disclosed |
| WO-2025038988-A1 | LAYERED METHODS FOR THE TREATMENT OF BACTERIAL INFECTION BASED ON THE COMBINATION OF HETEROLOGOUS VACCINATION AND ANTIBIOTIC THERAPY | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2025-02-20 | — | — | WO | disclosed |
| WO-1992007836-A1 | NOVEL SULFAMIDE DERIVATIVES, A METHOD FOR OBTAINING THEM AND THEIR USE AS A DRUG | SHIMI IBRAHIM RAOUF (FR) | 1992-05-14 | — | — | WO | disclosed |
| US-3996356-A | ANTIBACTERIAL | HOFFMANN-LA ROCHE INC. (US) | 1976-12-07 | — | — | US | disclosed |
| US-RE28636-E | Antibacterial composition containing 5-methyl-3-sulfanilamidoisoxazole and trimethoxybenyl pyrimidine | — | 1975-12-02 | — | — | US | disclosed |
| US-3881003-A | Compositions containing 3-sulfanilamido-4,5-dimethylisoxazole and a trimethoxybenzyl pyrimidine | HOFFMANN LA ROCHE | 1975-04-29 | — | — | US | disclosed |