Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17867147 | 0.72 | ALDH1A1 (0.37) | HPGDMAPTMEN1KMT2ATDP1 | |
| SCHEMBL6756483 | 0.72 | CFTR (0.35) | MEN1KMT2AALDH1A1GAACYP2C9 | |
| SCHEMBL28511938 | 0.70 | FTO (0.47) | HPGDMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10481379 | 0.67 | KMT2A (0.48) | HPGDMAPTMEN1KMT2ATDP1 | |
| SCHEMBL28503311 | 0.65 | FTO (0.44) | HPGDMAPTMEN1KMT2ATDP1 | |
| SCHEMBL14740590 | 0.64 | FTO (0.50) | HPGDMAPTMEN1KMT2ATDP1 | |
| SCHEMBL29372231 | 0.64 | ESR2 (0.44) | HPGDMAPTMEN1KMT2ATDP1 | |
| SCHEMBL29452872 | 0.64 | FTO (0.50) | HPGDMAPTMEN1KMT2ATDP1 | |
| SCHEMBL27189627 | 0.64 | FTO (0.43) | HPGDMAPTMEN1KMT2ATDP1 | |
| SCHEMBL754484 | 0.64 | MAOA (0.38) | ALDH1A1GAAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081044-A | Detection of hydrogen peroxide with optical indicator chalcogen compounds | MILES INC. (US) | 1992-01-14 | — | — | US | disclosed |
| US-4996332-A | On oxidation produce fluorescent signals in analytical systems | MILES INC. (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0121743-B1 | OPTICAL INDICATOR CHALCOGEN COMPOUNDS AND USE | MILES LABORATORIES, INC. (US) | 1987-09-09 | — | — | EP | disclosed |
| EP-0121743-A2 | Optical indicator chalcogen compounds and use | MILES LABORATORIES, INC. (US) | 1984-10-17 | — | — | EP | disclosed |