Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546080 | 1.00 | EPHX2 (0.46) | EPHX2ALOX5ALDH1A1LMNAPGR | |
| SCHEMBL9546170 | 0.82 | EPHX2 (0.38) | EPHX2ALOX5ALDH1A1PTGER2PTGER4 | |
| SCHEMBL9546172 | 0.82 | EPHX2 (0.38) | EPHX2ALOX5ALDH1A1PTGER2PTGER4 | |
| SCHEMBL9734666 | 0.79 | ALOX5 (0.45) | EPHX2ALOX5ALDH1A1LMNAOXER1 | |
| SCHEMBL9546183 | 0.78 | EPHX2 (0.42) | EPHX2ALOX5ALDH1A1OXER1CNR2 | |
| SCHEMBL9546184 | 0.78 | EPHX2 (0.42) | EPHX2ALOX5ALDH1A1OXER1CNR2 | |
| SCHEMBL9546146 | 0.75 | EPHX2 (0.41) | EPHX2ALOX5ALDH1A1LMNAOXER1 | |
| SCHEMBL9546144 | 0.75 | EPHX2 (0.41) | EPHX2ALOX5ALDH1A1LMNAOXER1 | |
| Methyl Oleate SCHEMBL25202566 | 0.70 | EPHX2 (0.73) | EPHX2ALOX5ALDH1A1LMNAPGR | |
| SCHEMBL8982713 | 0.70 | EPHX2 (0.73) | EPHX2ALOX5ALDH1A1LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |