Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.35 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.35 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.35 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.35 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.35 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.35 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.35 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546144 | 1.00 | EPHX2 (0.41) | EPHX2ALOX5OXER1CNR1CNR2 | |
| SCHEMBL9546184 | 0.84 | EPHX2 (0.42) | EPHX2ALOX5OXER1CNR1CNR2 | |
| SCHEMBL9546183 | 0.84 | EPHX2 (0.42) | EPHX2ALOX5OXER1CNR1CNR2 | |
| SCHEMBL9734666 | 0.81 | ALOX5 (0.45) | EPHX2ALOX5OXER1CNR1CNR2 | |
| SCHEMBL9546080 | 0.75 | EPHX2 (0.46) | EPHX2ALOX5OXER1CNR1CNR2 | |
| SCHEMBL9546075 | 0.75 | EPHX2 (0.46) | EPHX2ALOX5OXER1CNR1CNR2 | |
| Methyl Oleate SCHEMBL10455851 | 0.71 | EPHX2 (0.71) | EPHX2ALOX5OXER1CNR2SOAT1 | |
| Methyl Oleate SCHEMBL1069602 | 0.71 | EPHX2 (0.71) | EPHX2ALOX5OXER1CNR2SOAT1 | |
| SCHEMBL24751538 | 0.69 | EPHX2 (0.73) | EPHX2ALOX5OXER1CNR2SOAT1 | |
| Methyl Oleate SCHEMBL2052378 | 0.69 | EPHX2 (0.73) | EPHX2ALOX5OXER1CNR2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |