Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CFD | P00746 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 6/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11163374 | 0.90 | HTT (0.46) | TOP1THRBGAAALDH1A1TSHR | |
| SCHEMBL11155198 | 0.89 | THRB (0.49) | THRBGAAALDH1A1TSHRTDP1 | |
| SCHEMBL11166903 | 0.83 | MEN1 (0.41) | TOP1THRBGAAALDH1A1TSHR | |
| SCHEMBL28717635 | 0.81 | THRB (0.45) | THRBGAAALDH1A1THRAITGB3 | |
| SCHEMBL6221035 | 0.80 | GAA (0.56) | GAAALDH1A1TSHRTDP1NFKB1 | |
| SCHEMBL9360555 | 0.80 | GAA (0.56) | GAAALDH1A1TSHRTDP1NFKB1 | |
| SCHEMBL7658347 | 0.79 | TOP1 (0.47) | TOP1GAAALDH1A1TSHRTDP1 | |
| Methane SCHEMBL10372267 | 0.79 | GAA (0.54) | GAAALDH1A1TSHRTDP1NFKB1 | |
| SCHEMBL28377209 | 0.78 | ADORA3 (0.58) | GAAALDH1A1TSHRTDP1MAPK1 | |
| SCHEMBL717127 | 0.77 | PTGS2 (0.55) | TOP1ALDH1A1TSHRTDP1CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238061-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS | Banyu Pharmaceutical Co., Ltd. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4880797-A | THIAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-11-14 | — | — | US | claimed |
| EP-0238061-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-09-23 | — | — | EP | claimed |
| EP-0238061-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS | Banyu Pharmaceutical Co., Ltd. (JP) | 1992-10-21 | — | — | EP | disclosed |
| US-5001121-A | Cephalosporin compounds and pharmaceutical compositions thereof | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-19 | — | — | US | disclosed |
| US-4988687-A | Thiazoleoxyimineacetamido carboxymethylpyridinium derivatives of cephalosporins | BANYU PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-01-29 | — | — | US | disclosed |
| US-4956474-A | PHTHALIMIDOOXY OR AMINOXY COMPOUNDS FOR MAKING CEPHALOSPORINS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0360298-A2 | Intermediate compounds for use in the synthesis of cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |
| EP-0359291-A1 | Cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-21 | — | — | EP | disclosed |
| US-4904791-A | Cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| US-4880797-A | THIAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| US-4840945-A | ANTIBIOTICS EFFECTIVE AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-06-20 | — | — | US | disclosed |
| EP-0238061-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |
| EP-0197409-A1 | Cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-15 | — | — | EP | disclosed |
| WO-1986005786-A1 | CEPHALOSPORIN DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |