Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 2/20 | 0.67 |
| ▸ | FEN1 | P39748 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11635865 | 0.84 | ALDH1A1 (0.61) | ERCC5FEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL11631702 | 0.84 | ALDH1A1 (0.55) | ERCC5FEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL11725703 | 0.84 | ERCC5 (0.62) | ERCC5FEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL11635009 | 0.84 | KDM4E (0.52) | ERCC5FEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL11634177 | 0.82 | SLC9A1 (0.56) | ERCC5FEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL11805242 | 0.82 | ERCC5 (0.68) | ERCC5FEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL1286218 | 0.80 | ALDH1A1 (0.70) | ERCC5FEN1ALDH1A1HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL9478421 | 0.80 | ERCC5 (0.57) | ERCC5FEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL9478990 | 0.78 | ERCC5 (0.71) | ERCC5FEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL11826852 | 0.78 | ALDH1A1 (0.63) | ERCC5FEN1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035394-A | 5-Phenyl-2-furanyl-oxo or-hydroxy alkanoic acids and ethyl esters as gastric acid antisecretory agents | MORTON-NORWICH PRODUCTS, INC. (US) | 1977-07-12 | — | — | US | claimed |
| US-5091426-A | 5-PHENYL-2-FURAN KETONES AND USE AS ANTIEPILEPTIC AGENTS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0404232-A1 | The use of 5-phenyl-2-furan ketones as antiepileptic agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4035394-A | 5-Phenyl-2-furanyl-oxo or-hydroxy alkanoic acids and ethyl esters as gastric acid antisecretory agents | MORTON-NORWICH PRODUCTS, INC. (US) | 1977-07-12 | — | — | US | disclosed |