Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 9/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735159 | 0.70 | KDM5A (0.34) | — | |
| SCHEMBL9734357 | 0.70 | KDM5A (0.34) | — | |
| SCHEMBL30074982 | 0.66 | TRPA1 (0.47) | HTR3ATRPA1PROKR1HSD11B1 | |
| SCHEMBL218475 | 0.62 | HTR3A (0.59) | HTR3A | |
| SCHEMBL435619 | 0.62 | HTR3A (0.59) | HTR3A | |
| SCHEMBL19199720 | 0.61 | SLC6A4 (0.41) | — | |
| Hydrochloric Acid SCHEMBL18911747 | 0.61 | DRD2 (0.38) | — | |
| Methyl Alcohol SCHEMBL8471414 | 0.61 | SLC18A3 (0.56) | HTR3APROKR1 | |
| SCHEMBL8125540 | 0.60 | HTR3A (0.57) | HTR3A | |
| SCHEMBL127746 | 0.60 | HTR3A (0.57) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091539-A | Reacting an ozolyl cycloalkanone with Grignard reagent or alkali metal compound | SHIONOGI & CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |