Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735131 | 1.00 | ACE2 (0.38) | ACE2CTSLCTSKCTSSFKBP1A | |
| SCHEMBL9734738 | 0.97 | — | — | |
| SCHEMBL9736075 | 0.97 | — | — | |
| SCHEMBL7618670 | 0.85 | MMP2 (0.44) | — | |
| SCHEMBL14262421 | 0.84 | GRIN2B (0.46) | — | |
| SCHEMBL3054791 | 0.83 | NTSR1 (0.40) | — | |
| SCHEMBL3046330 | 0.82 | — | — | |
| SCHEMBL7618677 | 0.82 | — | — | |
| SCHEMBL7525973 | 0.81 | MMP2 (0.43) | — | |
| SCHEMBL7525987 | 0.81 | MMP2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166136-A | SPIROLACTAM CONTAINING PEPTIDES | GLAXO GROUP LIMITED (GB) | 1992-11-24 | — | — | US | disclosed |