Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16291117 | 0.85 | CYP3A4 (0.41) | ALDH1A1HPGDCHRM2CHRM3MAOA | |
| SCHEMBL13586897 | 0.83 | ALDH1A1 (0.43) | ALDH1A1USP2HPGDMAOACYP3A4 | |
| SCHEMBL13034130 | 0.83 | GAA (0.49) | NOTUMALDH1A1USP2HPGDCYP3A4 | |
| SCHEMBL27807653 | 0.81 | KDM4E (0.43) | ALDH1A1MAOACYP3A4CYP19A1TSHR | |
| SCHEMBL9767917 | 0.80 | GAA (0.39) | ALDH1A1HPGDCHRM2CHRM3MAOA | |
| SCHEMBL4917453 | 0.80 | NOTUM (0.42) | NOTUMALDH1A1USP2HPGDMAOA | |
| SCHEMBL10034916 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAOACYP3A4CYP19A1KDM4E | |
| SCHEMBL13586896 | 0.79 | ALDH1A1 (0.43) | ALDH1A1USP2MAOACYP3A4CYP19A1 | |
| SCHEMBL8326571 | 0.79 | LMNA (0.50) | ALDH1A1HPGDMAOACYP3A4TSHR | |
| SCHEMBL27835389 | 0.79 | TDP1 (0.44) | NOTUMALDH1A1HPGDMAOAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169428-A | Tetrahydrophthalimide derivative and herbicide composition containing same | TOSOH CORPORATION (JP) | 1992-12-08 | — | — | US | disclosed |
| EP-0323271-A1 | Tetrahydrophthalimide derivative and herbicide composition containing the same | Tosoh Corporation (JP) | 1989-07-05 | — | — | EP | disclosed |