Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767957 | 0.84 | GAA (0.37) | GAACHRM2CHRM3MAOAHTR2C | |
| SCHEMBL9735392 | 0.80 | NOTUM (0.42) | GAACHRM2CHRM3MAOAHTR2C | |
| SCHEMBL16291117 | 0.79 | CYP3A4 (0.41) | CHRM2CHRM3MAOAHTR2CCHRNA4 | |
| SCHEMBL9734886 | 0.75 | CYP3A4 (0.39) | GAACHRM2CHRM3MAOAHTR2C | |
| SCHEMBL8326571 | 0.73 | LMNA (0.50) | MAOAALDH1A1CYP3A4CYP1A2MEN1 | |
| SCHEMBL11316537 | 0.71 | CYP3A4 (0.46) | GAAKDM4EALDH1A1CYP3A4HTR2A | |
| SCHEMBL9767948 | 0.70 | CYP3A4 (0.38) | ALDH1A1CYP3A4CYP1A2MEN1KMT2A | |
| SCHEMBL4277534 | 0.69 | MAOA (0.44) | CHRM2CHRM3MAOAHTR2CCHRNA4 | |
| SCHEMBL7767699 | 0.69 | CYP3A4 (0.41) | GAACHRM2CHRM3MAOAHTR2C | |
| SCHEMBL282088 | 0.69 | CYP3A4 (0.52) | GAACHRM2CHRM3MAOAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013354-A | Tetrahydrophthalimido group, herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1991-05-07 | — | — | US | disclosed |