Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 4/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737198 | 0.86 | NAMPT (0.54) | TSHRMEN1KMT2ANAMPTAKR1C3 | |
| SCHEMBL630665 | 0.84 | RBP4 (0.56) | NAMPT | |
| SCHEMBL766268 | 0.84 | RBP4 (0.56) | NAMPT | |
| SCHEMBL766246 | 0.84 | RBP4 (0.56) | NAMPT | |
| SCHEMBL9735572 | 0.84 | ALDH1A1 (0.56) | TSHRKMT2ANAMPTAKR1C3 | |
| SCHEMBL9734955 | 0.84 | HTT (0.57) | MEN1KMT2ANAMPTMAPTNPSR1 | |
| SCHEMBL767039 | 0.83 | NAMPT (0.50) | TSHRMEN1KMT2ANAMPTAR | |
| SCHEMBL9735387 | 0.82 | NAMPT (0.67) | TSHRMEN1KMT2ANAMPTMAPT | |
| SCHEMBL7950882 | 0.79 | NAMPT (0.51) | TSHRMEN1KMT2ANAMPT | |
| SCHEMBL7950888 | 0.79 | NAMPT (0.51) | TSHRMEN1KMT2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |