Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736130 | 0.86 | NAMPT (0.61) | NAMPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL9735951 | 0.86 | NAMPT (0.61) | NAMPTKMT2AALDH1A1MEN1USP2 | |
| SCHEMBL9736530 | 0.84 | MAPT (0.61) | NAMPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL7950888 | 0.83 | NAMPT (0.51) | NAMPTTSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL7950882 | 0.83 | NAMPT (0.51) | NAMPTTSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL9734952 | 0.83 | NAMPT (0.52) | NAMPTKMT2AALDH1A1MEN1USP2 | |
| SCHEMBL9734450 | 0.83 | NAMPT (0.58) | NAMPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL9737198 | 0.83 | NAMPT (0.54) | NAMPTTSHRKMT2AMEN1USP2 | |
| SCHEMBL9736057 | 0.82 | POLB (0.65) | NAMPTTSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL9735403 | 0.82 | TSHR (0.60) | NAMPTTSHRKMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |