Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735487 | 0.79 | NPC1 (0.37) | NPC1MAPTRAB9ASMN1; SMN2IDO1 | |
| SCHEMBL30902518 | 0.70 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2GAAMPO | |
| SCHEMBL13676865 | 0.70 | IDO1 (0.52) | NPC1MAPTRAB9AIDO1SLC6A4 | |
| SCHEMBL9735484 | 0.69 | NPC1 (0.52) | NPC1SMN1; SMN2KDM4ETDP1GAA | |
| SCHEMBL10853860 | 0.67 | IDO1 (0.48) | NPC1MAPTRAB9ASMN1; SMN2IDO1 | |
| SCHEMBL8599131 | 0.67 | SLC2A1 (0.39) | NPC1GAAMCHR1 | |
| SCHEMBL3277991 | 0.66 | NPC1 (0.61) | NPC1MAPTKDM4ETDP1KMT2A | |
| SCHEMBL9734857 | 0.66 | EGFR (0.36) | NPC1KMT2AMEN1GAA | |
| Toluene SCHEMBL28554507 | 0.66 | NPC1 (0.47) | NPC1MAPTKMT2AMEN1GAA | |
| SCHEMBL9769674 | 0.65 | MAOA (0.36) | NPC1GAAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169428-A | Tetrahydrophthalimide derivative and herbicide composition containing same | TOSOH CORPORATION (JP) | 1992-12-08 | — | — | US | disclosed |
| EP-0323271-A1 | Tetrahydrophthalimide derivative and herbicide composition containing the same | Tosoh Corporation (JP) | 1989-07-05 | — | — | EP | disclosed |