Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | ME2 | P23368 | 1/20 | 0.49 |
| ▸ | ME1 | P48163 | 1/20 | 0.49 |
| ▸ | ME3 | Q16798 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | GPR183 | P32249 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735590 | 1.00 | MEN1 (0.57) | MEN1KMT2APOLBRAB9ALMNA | |
| SCHEMBL9735480 | 0.88 | MAPT (0.59) | POLBRAB9ALMNAGAASMN1; SMN2 | |
| SCHEMBL9735488 | 0.88 | MAPT (0.59) | POLBRAB9ALMNAGAASMN1; SMN2 | |
| SCHEMBL9735198 | 0.85 | GPR183 (0.58) | RAB9AGAASMN1; SMN2NPC1MAPT | |
| SCHEMBL9735192 | 0.85 | GPR183 (0.58) | RAB9AGAASMN1; SMN2NPC1MAPT | |
| SCHEMBL16599448 | 0.78 | KMT2A (0.89) | MEN1KMT2APOLBRAB9ALMNA | |
| SCHEMBL9734952 | 0.78 | NAMPT (0.52) | MEN1KMT2APOLBSMN1; SMN2HPGD | |
| SCHEMBL4456981 | 0.78 | KMT2A (0.89) | MEN1KMT2APOLBRAB9ALMNA | |
| SCHEMBL16599447 | 0.78 | KMT2A (0.89) | MEN1KMT2APOLBRAB9ALMNA | |
| SCHEMBL7950882 | 0.78 | NAMPT (0.51) | MEN1KMT2APOLBSMN1; SMN2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |